In Excellence We Believe
Manufacturing
Production Capacity
Vast production capacity that reaches up to 500 million tablets and 80 million capsules that qualifies the ADCAN to fulfill the requirements of different business partners. It has always been known that facilities and processes involved in pharmaceutical production impact significantly on the quality of the finished products.
ADCAN
Manufacturing Stages
STEP 1
Dispensing
STEP 2
Granulation
STEP 3
Compression
STEP 4
Encapsulation
STEP 5
Coating
STEP 6
Blistering
STEP 7
Packaging
STEP 8
Storage
Dispensing
A key part of the pharmaceutical manufacturing process will involve dispensing: the weighing and transfer of raw materials to containers for further processing and the similar transfer of processed powders to containers for onward shipment.
The demands of cGMP compliance dictate that these processes are carried out with zero risk of materials becoming cross contaminated, any escape of toxic substances or exposure to personnel.
Granulation
Granulation is a key processing step in the production of many solid-dosage drugs. It is often necessary to convert powdered drug formulations into a physical form that has improved flow & compaction characteristics to produce tablets with uniform content and consistent hardness and other properties.
The procedure of pharmaceutical granulation
is not the very same for all tablets. There can
be different issues depending on the density
or particle size within tablets, in addition to
other compatibility problems. Here the active
component might not mix with the excipient
and partition can take place.
Compression
Powered by IMA Active’s knowledge of the sector, designed with unique Italian style, built to deliver top-level performance, PREXIMA drives productivity to a higher level of efficiency and ensures optimal performance even with the most difficult-to-manage powders, keeping the tablet uniform in terms of weight and hardness.
- Fully Closed System
- Autoloading of Material (Pneumatic or Bin Lifting)
- Data Logging for each Operation
- Compression Pressure: up to 100KN
Coating
Tablet film coating is a common but critical process providing various functionalities to tablets, thereby meeting diverse clinical needs, and increasing the value of oral solid dosage forms. Tablet film coating is a technology-driven process, and the evolution of coated dosage forms relies on advancements in coating technology, equipment, analytical techniques, and coating materials.
Glatt coaters are ideal for film and sugar coating of tablets pellets granules and other formed products. At Adcan we have this time proven solution for refining the tablets capsules and pellets
Capsule Filling
Adapta: The Evolving Capsule Filler
The machine features an exceptional design flexibility: two of its dosing units are reversible/interchangeable giving the possibility of a plug and play shift between different machine configurations and filling combinations. The machine is designed to dose 3 products (up to 5 upon request) into the same capsule, reaching a speed of 100,000 capsules/hour.
The Adapta also has an indisputable efficiency as far as in-process control is concerned. With the appropriate options, total production control can be achieved thanks to individual check of product dosage and %100 control of gross and/or net weight.
Blistering
Adcan Pharma has state of the art blistering machine. TR200 is a double-row blister packaging machine, able to reach 350 blisters/minute, based on established technology which grants excellent production reliability together with quick and easy changeover and operator-friendly.
- Capacity: 350 blisters per min
- Data Logging
- Online with Cartoner Machine
- Alu, PVC & PVDC
- Inspection Camera by Antares Vision System
- Pin Hole Detection System
Packaging
IMA A83 is the perfect cartoning machine for blister packaging, as small-volume batches with very frequent changeovers can be linked to all blister machines. The machine has only one motor and is mechanically reliable with low-cost size parts due to adjustable devices.
- Data Logging
- Integrated with blistering machine
- 160 cartons per min
- Leaflet Detection
- Blister Detection
Storage
A pharmaceutical product’s quality is defined as pure, correctly identified, effective, and safe to use. The warehouse plays a pivotal role in manufacturing quality products, as it is responsible for all incoming goods (including labeling and packaging) and for releasing finished products, Therefore there are GMP rules in place to ensure the materials and the finished products are handled and stored properly while appropriate documentations is maintained.
Our spacious warehouse has the capacity to hold 1,700 pallets on a GMP racking system. The warehouse houses a sampling area with an innovative pneumatic tubing system. This tubing system has been specially designed to transport samples from the sampling area to the quality control facilities.